The only difference with Creative Cloud (vs Creative Suite) is that you install the apps from the cloud rather than via CD or DVD.
There is no way to use them without installing them to your desktop. I have been using Adobe Tools since Photoshop 1.0 and Illustrator 88 (and Aldus Freehand). The formats are still the same (.psd, .ai, .esp) with a few new formats since then.
I have not used them professionally in years, but I still maintain a license to freelance on the rare occasion and dabble a bit for fun. Functionally, they are basically the same tools they have always been, but with more bells and whistles (and more crossover).
I saw a news report today that said the armed deputy sheriff who was working at the school took a defensive position outside the school instead of doing his job protecting the students from the shooter.
I am disgusted.